E boetse e tsejoa e le dimethylaniline, mokelikeli o mafura o se nang 'mala ho isa ho o mosehla o bobebe, monko o halefisang, moeeng kapa tlas'a letsatsi o bonolo oa oxidation o sebelisoa Ze be deep. Boima bo amanang (20℃/4℃) 0.9555, ntlha ea ho hoamisa 2.0℃, ntlha ea ho belisa 193℃, ntlha ea flash (ho bula) 77℃, ntlha ea ho hotetsa 317℃, viscosity (25℃) 1.528 MPa ·s, refractive index (N20D) 1.5584. E qhibiliha ka har'a ethanol, ether, chloroform, benzene le li-solvents tse ling tsa organic. E ka qhala mefuta e fapaneng ea metsoako ea organic. E qhibiliha hanyane ka metsing. E ka tuka, e tla chesa mollong o bulehileng, mouoane le moeeng ho etsa motsoako o phatlohang, moeli o phatlohang oa 1.2% ~ 7.0% (vol). Chefo e phahameng, ho bola ho phahameng ha mocheso oa ho lokolloa ha khase ea aniline e chefo. E ka monngoa ka letlalo 'me ea chefo, LD501410mg/kg, mahloriso a phahameng ka ho fetisisa a lumelletsoeng moeeng ke 5mg/m3.

Mekhoa ea polokelo

1. Lintlha tsa Polokelo [25] Boloka ka tlung e pholileng, e nang le moea o kenang. Boloka hole le mollo le mocheso. Boloka setshelo se koetsoe. Se lokela ho bolokoa se arohane le li-acid, li-halogen le lik'hemik'hale tsa lijo, 'me ha sea lokela ho kopanngoa. Hlomella ka mefuta e fapaneng le bongata bo loketseng ba lisebelisoa tsa ho tima mollo. Sebaka sa polokelo se lokela ho hlomelloa ka lisebelisoa tsa kalafo ea tšohanyetso tse lutlang le thepa e loketseng ea polokelo.

2. E koetsoe ka teramo ea tšepe, 180kg ka barele. Boloka sebakeng se pholileng le se nang le moea o kenang. Boloka le ho e tsamaisa ho latela melao ea lintho tse tukang le tse chefo.

Mekhoa ea maiketsetso

1. Ka aniline le methanol moo ho nang le asiti ea sulfuric, ka lebaka la mocheso o phahameng le karabelo e phahameng ea khatello. Phallo ea ts'ebetso: 1. Kenya 790kg ea aniline, 625kg ea methanol le 85kg ea asiti ea sulfuric (100% ea ammonium) ho reactor, laola mocheso oa 210-215℃ le khatello ea 3.1MPa, u arabe ka lihora tse 4, ebe u lokolla khatello, u tšollele thepa ho karohano, u e nyenyefatse ka 30% sodium hydroxide, ema, 'me u arole letsoai le ka tlase la ammonium la quaternary. Ebe karabelo ea hydrolysis ho 160℃, 0.7-0.9MPa ka lihora tse 3, hydrolysate e hlahisoang le oli e ka holimo li kopantsoe le ho hlatsoa ka metsi le vacuum distillation ho fumana sehlahisoa se felileng.

2, ka methanol le aniline e le thepa e tala, tlas'a boemo ba methanol e feteletseng, khatello ea sepakapaka, 200-250℃, ka ho kopanya alumina catalyst. Kakaretso ea tšebeliso ea thepa e tala: aniline 790kg/t, methanol 625kg/t, sulfuric acid 85kg/t. Tokisetso ea laboratori e ka arabela aniline le trimethyl phosphate.

3. Aniline e tsoakiloeng le methanol (aniline ea N: N methanol ≈ 1:3) 'me e kenngoa ka har'a reactor e nang le catalyst ka lebelo la sebaka la 0.5h-1 ka pompo ea ho lekanya e sa buleng. Mokelikeli oa karabelo o kena pele karolong ea khalase ea karohano ea khase le mokelikeli, 'me mokelikeli o bokelletsoeng karolong e ka tlase ea karohano o ntšoa khafetsa bakeng sa tlhahlobo ea chromatographic.

4. Ka 2001, Univesithi ea Nankai le Tianjin Ruikai Science and Technology Development Co., Ltd ba ile ba theha ka kopanelo sesebelisoa se sebetsang hantle sa methylation ea aniline ho phethahatsa tlhahiso ea khase ea N, N-dimethylaniline. Ts'ebetso ena e tjena: Kamora hore aniline e metsi e tsoakoe le methanol ka tekanyo, e fetoloa mouoane toreng ea mouoane ebe e kenngoa ka har'a sesebelisoa sa tubular ka lebelo la sebaka la 0.5-1.0h-1 (bethe e tsitsitseng ea sesebelisoa sa tubular e na le sesebelisoa se tiileng sa nanometer se tšehetsoeng) bakeng sa tlhahiso e tsoelang pele ho 250-300℃ le khatello ea sepakapaka. Poelo ea DMA e kaholimo ho 96%.

Mokhoa oa ho hloekisa: hangata o na le aniline, N-methyl aniline le litšila tse ling. Nakong ea ho hloekisa, N, N-dimethylaniline e qhibiliha ka 40% ea sulfuric acid 'me ho etsoa distillation ea mouoane. Sodium hydroxide e eketsoa ho e etsa ea motheo. Distillation ea mouoane e tsoela pele. Distillate e arotsoe ka lera la metsi 'me e omisoa ka potassium hydroxide. E qhibilihisoa ka khatello ea sepakapaka moo ho nang le acetic anhydride. Distillate e hlatsuoa ka metsi ho tlosa bongata ba acetic anhydride, ebe e omisoa ka potassium hydroxide, e lateloe ke barium oxide le distillation e sa qobelloang molapong oa naetrojene. Mekhoa e meng ea ho hloekisa e kenyelletsa ho eketsa 10% acetic anhydride le reflux ka lihora tse 'maloa ho tlosa li-amine tsa mantlha le tsa bobeli. Kamora ho pholile, eketsa 20% ea hydrochloric acid e eketsehileng 'me u ntše ether. Lera la hydrochloric acid le entsoe alkaline ka ho eketsa alkali, ebe le ntšoa ka ether. Lera la ether le ile la omisoa ka potassium hydroxide ebe le qhibilihisoa tlas'a khatello tlas'a naetrojene. N, N-dimethylaniline e ka boela ea fetoloa ho ba picronate, ea etsoa hore e be ntlha e sa fetoheng ea ho qhibiliha ka tharollo e futhumetseng ea metsi ea 10% sodium hydroxide ho bola picronate. Ntša ka ether, hlatsoa ka metsi 'me u omelle ka mor'a ho qhibilihisa ka vacuum.

5. Aniline, methanol le sulfuric acid li kopanngoa ka tekanyo 'me lia kobeha ka har'a autoclave. Kamora hore sehlahisoa sa karabelo se fumanoe ka ho imolla khatello, alkali e eketsoa bakeng sa ho se hlole e le teng, karohano, ebe sehlahisoa se fumanoa ka ho qhala ka vacuum.

6. Karabelo ea methylation ea aniline le trimethyl phosphate e ka hlahisa N, N-dimethylaniline: ebe e ntšoa ka ether, e leng distillation e omileng.

7. N, N-dimethylaniline e ka etsoa ka ho eketsa motsoako oa aniline le methanol ka karolelano ea 1∶ 3.5 ka har'a bethe ea catalytic ea Cu-Mn kapa Cu-Zn-Cr Ziegler catalyst ho 280℃. N, N-dimethylaniline e hlahisoang e bokelloa ka har'a yuniti ea distillation ea lipoleiti tse 54 tse pakeng tsa 193 le 195℃ 'me e pakoa ka har'a libotlolo tsa khalase tse sootho. Bakeng sa ho lokisa chromatography N, N-dimethylaniline e hloekileng, naetrojene e ka ba khase e tsamaisang, ka har'a chromatography ea khase ea ho lokisa e nang le Ben 犅 yaku column e kentsoe tokiso ea N, N-dimethylaniline, ka karohano le pokello ea karolo e kholo ea karolo ea tlhōrō, ebe e kenngoa ka har'a seal ea ampoule ea khalase.

Morero o ka sehloohong

1. E 'ngoe ea lisebelisoa tsa mantlha tse tala bakeng sa tlhahiso ea lidae tsa motheo tsa letsoai (lidae tsa triphenyl methane, jj.) le lidae tsa motheo, mefuta e meholo ke alkaline e mosehla o khanyang, alkaline purple 5GN, alkaline green, alkaline lake blue, brilliant red 5GN, brilliant blue, jj. N, N-dimethylaniline indastering ea meriana bakeng sa tlhahiso ea cephalosporin V, sulfamilamide B-methoxymidine, sulfamilamide dimethoxymidine, fluorouracil, jj., indastering ea monko o monate bakeng sa tlhahiso ea vanillin, jj. 2. E sebelisoa e le solvent, tšepe e bolokang, e phekolang resin ea epoxy, e phekolang accelerator ea polyester resin, e thusang ho etsa polymerization ea metsoako ea ethylene, jj. E boetse e sebelisoa ho lokiseng lidae tsa motheo tsa triphenyl methane, lidae tsa azo le vanillin. 3. Sehlahisoa sena se sebelisoa e le catalyst bakeng sa ho etsa polasetiki ea foam ea polyurethane ka metsoako ea organic tin. E boetse e sebelisoa e le rabara vulcanization accelerator, libomo, thepa e tala ea meriana. Ke e 'ngoe ea lisebelisoa tsa mantlha tse tala bakeng sa tlhahiso ea lidae tse thehiloeng motheong (lidae tsa triphenyl methane, jj.) le lidae tsa motheo. Mefuta e meholo ke mosehla o khanyang oa motheo, pherese ea motheo BN, botala ba motheo, boputsoa ba letšeng la motheo, bofubelu bo khanyang ba 5GN, boputsoa bo khanyang, jj. N, N-dimethylaniline indastering ea meriana bakeng sa tlhahiso ea cephalosporin V, sulfamilamide N- methoxymidine, sulfamilamide – dimethoxymidine, fluorouracil, jj., indastering ea monko o monate bakeng sa tlhahiso ea vanillin, jj. 4. E sebelisoa e le accelerator ea ho phekola resin ea epoxy, resin ea polyester le sekhomaretsi sa anaerobic, e le hore sekhomaretsi sa anaerobic se ka phekoloa kapele. E ka boela ea sebelisoa e le solvent, catalyst bakeng sa polymerization ea metsoako ea ethylene, sesebelisoa sa ho boloka tšepe, sesebelisoa sa ultraviolet bakeng sa litlolo, sesebelisoa sa ho lemoha leseli, jj. E boetse e sebelisoa tlhahisong ea lidae tsa motheo, lidae tse hasaneng, lidae tsa asiti, lidae tse qhibilihang ka oli le linoko (vanillin) le lisebelisoa tse ling tse tala. 5. Reagent e sebediswang bakeng sa ho fumana nitrite ka photometric. E boetse e sebediswa e le solvent le ka ho kopanya dintho tse phelang. 6. E sebediswa e le dae intermediate, solvent, stabilizer, analytical reagent.